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Article

[Genetic polymorphism in human drug metabolism].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica - 1 Feb 1993

Yamazoe Y, Nagata K

Abstract excerpt

During the last decade, the influences of genetic factors on individual drug metabolizing capacity in humans have been characterized in fairly great detail at the molecular level. Debrisoquine/sparteine and mephenytoin polymorphisms are now known to be derived from defects in the human liver of specific forms of microsomal CYP (P450 or previously termed cytochrome P-450), CYP2D6 and CYP2C9 (2C18), respectively....

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Identifiers

PMID: 8454228
DOI: 10.1254/fpj.101.2_69

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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