Article
[Clinical significance of oxidation and acetylation genetic polymorphism in patients with Parkinson's disease].
Neurologia i neurochirurgia polska - 1 Jan 2000
Milejski P, Orzechowska-Juzwenko K, Kamienowski J, Horoch E, Niewiński P, Hurkacz M, Rzemisławska Z
Abstract excerpt
The relationship between genetically determined polymorphic oxidation and acetylation and susceptibility to some disease has aroused much interest. The aim of our study was to evaluate whether patients with Parkinson's disease differ from healthy persons in their ability to oxidize sparteine and acetylate sulfadimidine as model drugs. Oxidation and acetylation phenotypes were estimated in 50 patients with...
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