Article
[Clinical significance of oxidation and acetylation genetic polymorphism in patients with hyperthyreosis].
Endokrynologia Polska - 1 Jan 2000
Milejski Piotr, Orzechowska-Juzwenko Krystyna, Niewiński Przemysław, Hurkacz Magdalena, Czarnik-Matusewicz Henryk, Forkasiewicz Zdzisław, Dawiskiba Janusz, Bednarz Wiktor, Domosławski Paweł
Abstract excerpt
INTRODUCTION: The relationship between genetically determined polymorphic oxidation and acetylation and susceptibility to some disease was aroused much interest. The aim of our study was to evaluate whether patients with hyperthyreosis differ from healthy persons in their ability to oxidize sparteine and acetylate sulphadimidine as model drugs. Oxidation and acetylation were estimated in 48 patients with...
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