Early behavioral development of mice is affected by staggerer mutation as soon as postnatal day three.

Abstract excerpt

Staggerer is a neurological mutation of mice that affects the development of the central nervous system and causes abnormal behaviors. The staggerer cerebellum is already abnormal at birth and as the animal grows up there is a progressive loss of granule cells which have all disappeared by day 28. The earliest behavioral disturbance observed is a motor deficiency which occurs between 10 and 15 days-i.e. several...

Topics

• Animals
• Avoidance Learning
• Behavior, Animal
• Cerebellum
• Locomotion
• Mice
• Mice, Inbred C57BL
• Mice, Neurologic Mutants
• Mutation
• Postural Balance
• Vocalization, Animal