Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell loss in the inferior olive of the staggerer mutant mouse is an indirect effect of the gene.

Journal of neurogenetics - 1 Aug 1990

Zanjani H S, Mariani J, Herrup K

Abstract excerpt

Staggerer (sg) is an autosomal recessive mutation in mouse that causes severe cerebellar atrophy. In this mutant, the Purkinje cell (PC) number is reduced by about 75% and the remaining Purkinje cells have a reduced dendritic arbor and an ectopic location. Previous analysis of staggerer chimeras has demonstrated that the Purkinje cell phenotypes are all direct consequences of the cell-autonomous action of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Count
Share to Chimera
Share to Genes, Recessive

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Neurologic Mutants

Share to Phenotype

Source

Identifiers

PMID: 2231177
DOI: 10.3109/01677069009107113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell loss in the inferior olive of the staggerer mutant mouse is an indirect effect of the gene.PMID 2231177Read ↗

Stunted morphologies of cerebellar Purkinje cells in lurcher and staggerer mice are cell-intrinsic effects of the mutant genes.Semantic proximity Read ↗

The Lurcher cerebellar mutant phenotype is not expressed on a staggerer mutant background.Semantic proximity Read ↗

A comparative study of Purkinje cells in two RORalpha gene mutant mice: staggerer and RORalpha(-/-).Semantic proximity Read ↗

Neuronal differentiation and developmental characteristics in the dentate gyrus of staggerer mutant mice.Semantic proximity Read ↗

Cerebellar Purkinje cell loss during life span of the heterozygous staggerer mouse (Rora(+)/Rora(sg)) is gender-related.Semantic proximity Read ↗

Purkinje cell loss in heterozygous staggerer mutant mice during aging.Semantic proximity Read ↗

Evidence of spinocerebellar mossy fiber segregation in the juvenile staggerer cerebellum.Semantic proximity Read ↗

Progressive atrophy of cerebellar Purkinje cell dendrites during aging of the heterozygous staggerer mouse (Rora(+/sg)).Semantic proximity Read ↗

Developmental analysis of the external granular layer in the <i>Meander tail</i> mutant mouse: Do cerebellar microneurons have independent progenitors?Semantic proximity Read ↗

The Spontaneous Ataxic Mouse Mutant Tippy is Characterized by a Novel Purkinje Cell Morphogenesis and Degeneration Phenotype.Semantic proximity Read ↗

Orphan nuclear receptor ROR alpha-deficient mice display the cerebellar defects of staggerer.Semantic proximity Read ↗

Experimental Sey mouse chimeras reveal the developmental deficiencies of Pax6-null granule cells in the postnatal cerebellum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.