Stunted morphologies of cerebellar Purkinje cells in lurcher and staggerer mice are cell-intrinsic effects of the mutant genes.

doi:10.1002/cne.903570107

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Article

Stunted morphologies of cerebellar Purkinje cells in lurcher and staggerer mice are cell-intrinsic effects of the mutant genes.

The Journal of comparative neurology - 19 Jun 1995

Soha J M, Herrup K

Abstract excerpt

Purkinje cells in the neurological mutants lurcher and staggerer exhibit a number of abnormal properties; mutant<==>wild-type chimeras have shown that these properties are direct effects of the mutant gene. What has remained unexplored are the numerous dendritic abnormalities that the two mutant...

Topics

Animals
Base Sequence
Chimera
Dendrites
Genotype
Mice
Mice, Neurologic Mutants
Molecular Sequence Data
Purkinje Cells

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