Article
Association of rheumatoid arthritis with an amino acid allelic variation of the T cell receptor.
Arthritis and rheumatism - 1 Aug 1997
Cornélis F, Hardwick L, Flipo R M, Martinez M, Lasbleiz S, Prud'homme J F, Tran T H, Walsh S, Delaye A, Nicod A, Loste M N, Lepage V, Gibson K, Pile K, Djoulah S, Danzé P M, Lioté F, Charron D, Weissenbach J, Kuntz D, Bardin T, Wordsworth B P
Abstract excerpt
OBJECTIVE: To investigate allelic variations of T cell receptor residues for a contribution to rheumatoid arthritis (RA) susceptibility. METHODS: We conducted an RA case-control study involving 1,579 northwest Europeans: 766 patients with erosive and rheumatoid factor-positive disease and 813 con...
Topics
- Alleles
- Arthritis, Rheumatoid
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Genetic Variation
- Genotype
- Humans
- Polymorphism, Single-Stranded Conformational
- Receptors, Antigen, T-Cell, alpha-beta