Article
HLA and T cell receptor beta-chain DNA polymorphisms identify a distinct subset of patients with pauciarticular-onset juvenile rheumatoid arthritis.
Arthritis and rheumatism - 1 May 1994
Charmley P, Nepom B S, Concannon P
Abstract excerpt
OBJECTIVE: To evaluate and extend upon a reported association of a T cell receptor (TCR) V beta coding region polymorphism with pauciarticular-onset juvenile rheumatoid arthritis (JRA). METHODS: TCR V beta 6.1 genotypes and haplotypes in JRA and control groups were determined by DNA amplification...
Topics
- Arthritis, Juvenile
- Base Sequence
- DNA
- Gene Amplification
- Genotype
- HLA Antigens
- Haplotypes
- Humans
- Molecular Sequence Data
- Pedigree
- Point Mutation
- Polymorphism, Genetic
