Article
An association between the CTLA4 exon 1 polymorphism and early rheumatoid arthritis with autoimmune endocrinopathies.
Rheumatology (Oxford, England) - 1 Feb 2002
Vaidya B, Pearce S H S, Charlton S, Marshall N, Rowan A D, Griffiths I D, Kendall-Taylor P, Cawston T E, Young-Min S
Abstract excerpt
OBJECTIVE: To examine the allelic association of the single nucleotide polymorphism (CTLA4A/G) in exon 1 of the cytotoxic T lymphocyte antigen-4 (CTLA4) gene with early rheumatoid arthritis (RA). METHODS: One hundred and twenty-three unrelated white probands with early RA from the north-east of England and 349 local ethnically matched controls were studied. The CTLA4A/G polymorphism was genotyped with a...
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