Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced expression of a human V beta 6.1 T-cell receptor allele.

Proceedings of the National Academy of Sciences of the United States of America - 15 May 1993

Luyrink L, Gabriel C A, Thompson S D, Grom A A, Maksymowych W P, Choi E, Glass D N

Abstract excerpt

We have previously described an allelic polymorphism in the V beta 6.1 T-cell receptor gene. The V beta 6.1B allele is associated with disease in a subgroup of patients with juvenile rheumatoid arthritis. Limited sequence data demonstrated nucleotide differences that resulted in two amino acid changes between the two alleles in positions predicted to be important in major histocompatibility complex/antigen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Cloning, Molecular

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 8506275
DOI: 10.1073/pnas.90.10.4369
PMCID: PMC46512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced expression of a human V beta 6.1 T-cell receptor allele.PMID 8506275Read ↗

HLA and T cell receptor beta-chain DNA polymorphisms identify a distinct subset of patients with pauciarticular-onset juvenile rheumatoid arthritis.Semantic proximity Read ↗

T-cell receptor BV6S1 null alleles and HLA-DR1 haplotypes in polyarticular outcome juvenile rheumatoid arthritis.Semantic proximity Read ↗

Identification of a predominant sequence variant of the T-cell receptor TCRBC1 gene.Semantic proximity Read ↗

The human T-cell receptor variable gene segment TCRBV6S1 has two null alleles.Semantic proximity Read ↗

Lack of association with T-cell receptor TCRBV6S1*2 allele in HLA-DQA1*0101-positive Norwegian juvenile chronic arthritis patients.Semantic proximity Read ↗

Allelic variations in the human T cell receptor V beta 6.7 gene products.Semantic proximity Read ↗

Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritisSemantic proximity Read ↗

Coding region polymorphisms of human T-cell receptor V beta 6.9 and V beta 21.4.Semantic proximity Read ↗

Organization, polymorphism, and expression of the human T-cell receptor AV1 subfamily.Semantic proximity Read ↗

Silent allelic variants of a T-cell receptor V beta 12 gene are present in diverse human populations.Semantic proximity Read ↗

Association of rheumatoid arthritis with an amino acid allelic variation of the T cell receptor.Semantic proximity Read ↗

A functionally significant allelic polymorphism in a T cell receptor V beta gene segment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.