Article
Analysis of a T-cell receptor V beta segment implicated in susceptibility to rheumatoid arthritis: V beta 2 germline polymorphism does not encode susceptibility.
Annals of the rheumatic diseases - 1 Dec 1993
Pile K, Wordsworth P, Lioté F, Bardin T, Bell J, Cornélis F
Abstract excerpt
OBJECTIVES: The assessment of allelic polymorphism of the T cell receptor gene segment, TCRBV2S1, in rheumatoid arthritis. METHODS: A total of 136 patients with rheumatoid arthritis (RA) (ACR criteria) and 150 controls were TCRBV2S1 genotyped using a nested PCR amplification strategy followed by...
Topics
- Alleles
- Arthritis, Rheumatoid
- Base Sequence
- DNA, Single-Stranded
- Disease Susceptibility
- Genotype
- Humans
- Molecular Sequence Data
- Polymorphism, Genetic
- Receptors, Antigen, T-Cell