Article
Molecular characterization of HIV viruses generated after in vivo ligation.
Journal of virological methods - 1 Jul 1997
Guillon C, Oriol G, Gruters R A
Abstract excerpt
During the course of infection, human immunodeficiency virus type 1 (HIV-1) displays wide genotypic and phenotypic differences. Construction of chimeric viruses is useful to determine the genotypic basis that underlies phenotypic variations, but the procedure is time-consuming. Previously, it has been shown that co-transfection of truncated hemi-genomic HIV-1 proviral DNA can lead to generation of full-length...
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