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Article

Effects of mutations in the human immunodeficiency virus type 1 Gag gene on RNA packaging and recombination.

Journal of virology - 1 May 2006

Nikolaitchik Olga, Rhodes Terence D, Ott David, Hu Wei-Shau

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) recombination occurs during reverse transcription when parts of the two co-packaged RNAs are used as templates for DNA synthesis. It was previously hypothesized that HIV-1 Gag polyproteins preferentially encapsidate the RNA from which they were translated (cis-packaging hypothesis). This hypothesis implies that mutants encoding Gag that cannot efficiently package viral...

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Identifiers

PMID: 16641262
DOI: 10.1128/JVI.80.10.4691-4697.2006
PMCID: PMC1472086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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