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Article

Cotransfection of HIV-1 molecular clones with restricted cell tropism may yield progeny virus with altered phenotype.

AIDS research and human retroviruses - 1 Apr 1993

Tan W, Fredriksson R, Björndal A, Balfe P, Fenyö E M

Abstract excerpt

Seven infectious molecular clones were obtained from a human immunodeficiency virus type 1 isolate with rapid/high replicative capacity. Biological characterization of progeny viruses obtained after transfection of clones into peripheral blood mononuclear cells showed that six clones yielded virus with restricted cell tropism, whereas one clone yielded virus able to replicate in cell lines. Although transfection...

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Identifiers

PMID: 8512747
DOI: 10.1089/aid.1993.9.321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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