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Article

DNA mismatch repair gene mutations in human cancer.

Environmental health perspectives - 1 Jun 1997

Peltomäki P

Abstract excerpt

A new pathogenetic mechanism leading to cancer has been delineated in the past 3 years when human homologues of DNA mismatch repair (MMR) genes have been identified and shown to be involved in various types of cancer. Germline mutations of MMR genes cause susceptibility to a hereditary form of colon cancer, hereditary nonpolyposis colon cancer (HNPCC), which represents one of the most common syndromes associated...

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Identifiers

PMID: 9255561
DOI: 10.1289/ehp.105-1470030
PMCID: PMC1470030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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