Article
Update on Hereditary Colorectal Cancer.
Anticancer research - 1 Sept 2016
DA Silva Felipe Carneiro, Wernhoff Patrik, Dominguez-Barrera Constantino, Dominguez-Valentin Mev
Abstract excerpt
In the past two decades, significant advances have been made in our understanding of colorectal (CRC) tumors with DNA mismatch (MMR) repair deficiency. The knowledge from molecular and genetic alterations in a variety of clinical conditions has refined the disease terminology and classification. Hereditary non-polyposis colorectal cancer (HNPCC) encompasses a spectrum of conditions that have significant...
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