Article
DNA mismatch repair and colorectal cancer.
The Journal of pathology - 1 Jun 1998
Toft N J, Arends M J
Abstract excerpt
Colorectal cancer is the second commonest malignancy in the western world, accounting for 20,000 deaths in the U.K. per year. Over the last 10 years, great strides have been made in our understanding of the molecular controls governing the transition from normal mucosa, through adenoma, and final...
Topics
- Animals
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- DNA Repair
- DNA Replication
- DNA-Binding Proteins
- Humans
- Mice
- Microsatellite Repeats
- MutS Homolog 2 Protein
- Mutation
- Proto-Oncogene Proteins