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Article

DNA mismatch repair and colorectal cancer.

The Journal of pathology - 1 Jun 1998

Toft N J, Arends M J

Abstract excerpt

Colorectal cancer is the second commonest malignancy in the western world, accounting for 20,000 deaths in the U.K. per year. Over the last 10 years, great strides have been made in our understanding of the molecular controls governing the transition from normal mucosa, through adenoma, and finally to carcinoma. This review focuses on the recently discovered DNA mismatch repair pathway and its role in the...

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Identifiers

PMID: 9713337
DOI: 10.1002/(SICI)1096-9896(199806)185:2<123::AID-PATH62>3.0.CO;2-P

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