DNA mismatch repair and cancer.

doi:10.1016/0016-5085(95)90660-6

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Article

DNA mismatch repair and cancer.

Gastroenterology - 1 Nov 1995

Chung D C, Rustgi A K

Abstract excerpt

The genetic basis of cancer involves certain classes of genes, particularly oncogenes, tumor-suppressor genes, and DNA mismatch repair genes. Originally identified in bacteria and yeast, the human homologues of DNA mismatch repair genes have been implicated in the pathogenesis of the hereditary n...

Topics

Colonic Neoplasms
Colorectal Neoplasms, Hereditary Nonpolyposis
DNA Damage
DNA Repair
Humans
Mutation
Neoplasms
Oncogenes

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