How common are common fragile sites: variation of aphidicolin-induced chromosomal fragile sites in a population of the deer mouse (Peromyscus maniculatus).

doi:10.1007/s004390050487

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Article

How common are common fragile sites: variation of aphidicolin-induced chromosomal fragile sites in a population of the deer mouse (Peromyscus maniculatus).

Human genetics - 1 Aug 1997

McAllister B F, Greenbaum I F

Abstract excerpt

Aphidicolin (APC)-induced chromosomal gaps and breaks were analyzed for ten deer mice (Peromyscus maniculatus) from a natural population. The FSM statistical methodology was used to identify fragile sites as chromosomal loci exhibiting significantly non-random numbers of gaps/breaks in each individual and enabled an assessment of variation in fragile sites among the individuals. The individual deer mice exhibited...

Topics

Animals
Aphidicolin
Chromosome Aberrations
Chromosome Banding
Chromosome Fragile Sites
Chromosome Fragility
Chromosome Inversion
Genetic Variation
Peromyscus

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Open in PubMed

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PMID: 9254846
DOI: 10.1007/s004390050487

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