Chromosomal fragile site expression in dogs: I. Breed specific differences.

doi:10.1002/ajmg.1320400219

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Article

Chromosomal fragile site expression in dogs: I. Breed specific differences.

American journal of medical genetics - 1 Aug 1991

Stone D M, Jacky P B, Hancock D D, Prieur D J

Abstract excerpt

Peripheral blood lymphocytes from clinically normal Doberman pinscher and boxer dogs were cultured for folate-sensitive and, in preliminary studies, aphidicolin-inducible fragile site expression. Both autosomal and X chromosomal fragile sites were observed in canine cells cultured under folate/thymidine depletion and in cells cultured in medium containing aphidicolin. Results from the three dogs evaluated for...

Topics

Aging
Animals
Aphidicolin
Breeding
Cells, Cultured
Chromosome Fragile Sites
Chromosome Fragility
Culture Media
Diterpenes
Dogs
Female
Folic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Lymphocytes

Male

Risk

Sex Factors

X Chromosome

Source

Open in PubMed

Identifiers

PMID: 1910263
DOI: 10.1002/ajmg.1320400219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1910263-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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