Article
Chromosomal fragile site expression in dogs: I. Breed specific differences.
American journal of medical genetics - 1 Aug 1991
Stone D M, Jacky P B, Hancock D D, Prieur D J
Abstract excerpt
Peripheral blood lymphocytes from clinically normal Doberman pinscher and boxer dogs were cultured for folate-sensitive and, in preliminary studies, aphidicolin-inducible fragile site expression. Both autosomal and X chromosomal fragile sites were observed in canine cells cultured under folate/thymidine depletion and in cells cultured in medium containing aphidicolin. Results from the three dogs evaluated for...
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