Article
Links between chromatin structure, DNA repair and chromosome fragility.
Mutation research - 3 Aug 1998
Surrallés J, Puerto S, Ramírez M J, Creus A, Marcos R, Mullenders L H, Natarajan A T
Abstract excerpt
This paper is a brief overview of the studies we have recently conducted to unravel how chromatin structure and DNA repair modulate the fragility of diverse chromosomes and chromosomal regions. We have employed a combination of molecular cytogenetic techniques, including interphase and metaphase multicolour FISH, reverse FISH with CpG-rich probes or repaired DNA fractions, and several combinations of FISH and...
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