Links between chromatin structure, DNA repair and chromosome fragility.

doi:10.1016/s0027-5107(98)00093-1

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Article

Links between chromatin structure, DNA repair and chromosome fragility.

Mutation research - 3 Aug 1998

Surrallés J, Puerto S, Ramírez M J, Creus A, Marcos R, Mullenders L H, Natarajan A T

Abstract excerpt

This paper is a brief overview of the studies we have recently conducted to unravel how chromatin structure and DNA repair modulate the fragility of diverse chromosomes and chromosomal regions. We have employed a combination of molecular cytogenetic techniques, including interphase and metaphase...

Topics

Animals
Chromatin
Chromosome Aberrations
Chromosome Breakage
Chromosome Fragile Sites
Chromosome Fragility
Chromosomes
Cricetinae
DNA Damage
DNA Repair
Histones
Humans
Mutation

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