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Article

Chromosomal fragile sites and relationship between genetic predisposition to small cell lung cancer.

Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 2002

Karadağ M, Tunca B, Ceçener G, Egeli U, Ozyardimci N, Ege E, Gözü O

Abstract excerpt

Fragile sites are non-staining gaps and breaks on mammalian chromosomes. Several investigators have pointed out that these sites may act as factors that predispose to specific chromosomal rearrangements that are present in some cancer cases. The expression of common fragile sites induced by aphidicolin (Apc) was evaluated on prometaphase chromosomes obtained from the peripheral blood lymphocytes of 15 patients...

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Identifiers

PMID: 11754385
DOI: 10.1002/tcm.1036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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