Article
Common fragile site expression and genetic predisposition to breast cancer.
Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 1998
Ceçener G, Egeli U, Taşdelen I, Tunca B, Duman H, Kizil A
Abstract excerpt
The expression of common fragile sites induced by aphidicolin and caffeine was evaluated on prometaphase obtained from the peripheral blood lymphocytes of 35 women with breast cancer, their 35 clinically healthy female family members, and 20 sex- and age-matched normal controls. As a result of the cytogenetic and statistical evaluation, the number of damaged cells, chromosomal aberrations, and expression...
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