Article
Serine phosphorylation site of the 46-kDa mannose 6-phosphate receptor is required for transport to the plasma membrane in Madin-Darby canine kidney and mouse fibroblast cells.
Molecular biology of the cell - 1 Apr 1997
Breuer P, Körner C, Böker C, Herzog A, Pohlmann R, Braulke T
Abstract excerpt
Up to 4% of the human 46-kDa mannose 6-phosphate receptor (MPR46) expressed in Madin-Darby canine kidney (MDCK) cells are localized at the cell surface. At steady state, the expression of MPR46 on the apical surface of filter-grown MDCK cells is about sixfold lower than on the basolateral surface...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Biological Transport
- Cell Membrane
- Cell Polarity
- Cells, Cultured
- Dogs
- Embryo, Mammalian
- Fibroblasts
- Humans
- Kidney
- Mice
- Molecular Sequence Data
- Mutation