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Article

Extensive mannose phosphorylation on leukemia inhibitory factor (LIF) controls its extracellular levels by multiple mechanisms.

The Journal of biological chemistry - 15 Jul 2011

Barnes Jarrod, Lim Jae-Min, Godard Anne, Blanchard Frédéric, Wells Lance, Steet Richard

Abstract excerpt

In addition to soluble acid hydrolases, many nonlysosomal proteins have been shown to bear mannose 6-phosphate (Man-6-P) residues. Quantification of the extent of mannose phosphorylation and the relevance to physiological function, however, remain poorly defined. In this study, we investigated the mannose phosphorylation status of leukemia inhibitory factor (LIF), a previously identified high affinity ligand for...

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Identifiers

PMID: 21613225
DOI: 10.1074/jbc.M111.221432
PMCID: PMC3137060

Genes

LIF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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