Absence of mutations in the transforming growth factor-beta type II receptor in sporadic lung cancers with microsatellite instability and rare H-ras1 alleles.

doi:10.1093/carcin/18.7.1427

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Article

Absence of mutations in the transforming growth factor-beta type II receptor in sporadic lung cancers with microsatellite instability and rare H-ras1 alleles.

Carcinogenesis - 1 Jul 1997

Takenoshita S, Hagiwara K, Gemma A, Nagashima M, Ryberg D, Lindstedt B A, Bennett W P, Haugen A, Harris C C

Abstract excerpt

The transforming growth factor-beta type II receptor (RII) is commonly mutated in colon and gastric cancers with microsatellite instability (MI). We utilized our series of lung cancers with MI and rare alleles of the H-ras1 gene to determine the association between MI and RII mutations and search...

Topics

Alleles
Genes, ras
Humans
Lung Neoplasms
Microsatellite Repeats
Mutation
Receptors, Transforming Growth Factor beta

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