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Article

Modulation of kinase activities in dauers and in long-lived mutants of Caenorhabditis elegans.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jul 1997

Vanfleteren J R, De Vreese A

Abstract excerpt

Mutant alleles of the genes age-1 and daf-2 that lengthen life span (Age phenotype) of Caenorhabditis elegans cause higher protein kinase (PKA, PKC, PTK) activity levels in senescing worms relative to wild-type. Elevated levels of PKA and PTK were also present in dauer larvae, developmentally arrested juveniles specialized for long-term survival, relative to L3 larvae, the alternative developmental stage. PKC...

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PMID: 9224426
DOI: 10.1093/gerona/52a.4.b212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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