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Article

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans.

Nature - 8 Aug 1996

Morris J Z, Tissenbaum H A, Ruvkun G

Abstract excerpt

A pheromone-induced neurosecretory pathway in Caenorhabditis elegans triggers developmental arrest and an increase in longevity at the dauer diapause stage. The gene age-1 is required for non-dauer development and normal senescence. age-1 encodes a homologue of mammalian phosphatidylinositol-3-OH...

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PMID: 8700226
DOI: 10.1038/382536a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8700226-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans.PMID 8700226Read ↗

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