Article
Transgenic C. elegans dauer larvae expressing hookworm phospho null DAF-16/FoxO exit dauer.
PloS one - 1 Jan 2011
Gelmedin Verena, Brodigan Thomas, Gao Xin, Krause Michael, Wang Zhu, Hawdon John M
Abstract excerpt
Parasitic hookworms and the free-living model nematode Caenorhabtidis elegans share a developmental arrested stage, called the dauer stage in C. elegans and the infective third-stage larva (L3) in hookworms. One of the key transcription factors that regulate entrance to and exit from developmental arrest is the forkhead transcription factor DAF-16/FoxO. During the dauer stage, DAF-16 is activated and localized in...
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