Article
Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses.
Cell calcium - 1 Jun 1997
Collatz M B, Rüdel R, Brinkmeier H
Abstract excerpt
The effect of the membrane-permeant calcium chelator 1,2-bis-(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl) ester (BAPTA/AM) on ionomycin-induced cellular calcium overload was studied in single differentiated NH15-CA2 neuroblastoma x glioma hybrid cells. To monitor [Ca2+]i we used the fluorescent indicator Fura-2. Preincubation of the cells with 3 microM BAPTA/AM reduced the number of...
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