Article
Retinoic acid induction of calcium channel expression in human NT2N neurons.
Biochemical and biophysical research communications - 18 Jun 1998
Gao Z Y, Xu G, Stwora-Wojczyk M M, Matschinsky F M, Lee V M, Wolf B A
Abstract excerpt
Ca2+ channel expression and regulation of intracellular Ca2+ homeostasis were studied during retinoic acid (RA)-induced differentiation of the human teratocarcinoma cell line Ntera 2/C1.D1 (NT2- cells) into NT2N neurons, a unique model of human neurons in culture. The cytosolic Ca2+ level of undifferentiated NT2- cells was low (75 +/- 5 nM) and stable under basal conditions, and it was only marginally decreased...
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