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Article

Sigma Ligand-mediated Cytosolic Calcium Modulation in BV2 Microglia Cells

2024-11-20

Abstract excerpt

While initially protective, prolonged neuroinflammation can lead to a disrupted brain microenvironment and neurodegenerative diseases. Microglia cells are the primary regulators of neuroinflammation, with anti- or pro-inflammatory phenotypes. Just as microglia are crucial in neuroinflammation, calcium is a crucial regulator in the activation of the microglia. Intracellular calcium dynamics can be modulated by smal...

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Identifiers and source

Literature Corpus work
e18a54d7-0c8d-5556-bf48-3809abd5ef9e
DOI
10.1101/2024.11.18.624024
Open publication

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Sigma Ligand-mediated Cytosolic Calcium Modulation in BV2 Microglia CellsDOI 10.1101/2024.11.18.624024
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