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Article

Up-regulation of Ca2+ influx mediated by store-operated channels in HL60 cells induced to differentiate by 1 alpha,25-dihydroxyvitamin D3.

Journal of cellular physiology - 1 Sept 1997

Gardner J P, Balasubramanyam M, Studzinski G P

Abstract excerpt

The physiologically active form of vitamin D, 1 alpha,25-dihydroxyvitamin D3 (1,25D3), induces promyelocytic HL60 cells to differentiate towards monocyte-like cells. During this differentiation increased cytosolic calcium (Cai2+) and expression of surface receptors for chemotactic factors "prime" the cell for the activation of monocyte functions and the triggering of the respiratory burst pathway. We examined...

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Identifiers

PMID: 9284948
DOI: 10.1002/(SICI)1097-4652(199709)172:3<284::AID-JCP2>3.0.CO;2-K

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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