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Article

Role of protein kinase A in the regulation of cytosolic free calcium in human osteoblast-like SaOS-2 cells.

The American journal of physiology - 1 Feb 1993

Fukayama S, Tashjian A H, Bringhurst F R

Abstract excerpt

We have used wild-type and adenosine 3',5'-cyclic monophosphate (cAMP)-resistant mutant osteoblast-like SaOS-2 cells to investigate the role of protein kinase A (PKA) in the regulation of cytosolic free Ca2+ concentration ([Ca2+]i). Basal levels of [Ca2+]i were the same in wild-type (127 +/- 6.1 nM) and transfected (117 +/- 6.8 nM) SaOS-2 cells, although 45Ca2+ efflux was slower in the transfected cells. In...

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Identifiers

PMID: 8383434
DOI: 10.1152/ajpcell.1993.264.2.C464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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