Article
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice.
Science (New York, N.Y.) - 11 Jul 1997
Lindahl P, Johansson B R, Levéen P, Betsholtz C
Abstract excerpt
Platelet-derived growth factor (PDGF)-B-deficient mouse embryos were found to lack microvascular pericytes, which normally form part of the capillary wall, and they developed numerous capillary microaneurysms that ruptured at late gestation. Endothelial cells of the sprouting capillaries in the m...
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