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Article

Pericytes and the Pathogenesis of Diabetic Retinopathy

1 Oct 2002

Abstract excerpt

Pericytes provide vascular stability and control endothelial proliferation. Pericyte loss, microaneurysms, and acellular capillaries are characteristic for the diabetic retina. Platelet-derived growth factor (PDGF)-B is involved in pericyte recruitment, and brain capillaries of mice with a genetic ablation of PDGF-B show pericyte loss and microaneurysms. We investigated the role of capillary coverage with...

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Identifiers

PMID: 12351455
DOI: 10.2337/diabetes.51.10.3107

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