Article
Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America - 8 Jul 1997
Abramova N A, Russell J, Botchan M, Li R
Abstract excerpt
Replication protein A (RPA) is required for both DNA replication and nucleotide excision repair. Previous studies have shown that RPA interacts with the tumor suppressor p53. Herein, we have mapped a 20-amino acid region in the N-terminal part of p53 that is essential for its binding to RPA. This...
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