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Article

Frequency of replication errors in colorectal cancer and their association with family history.

Gut - 1 Oct 1998

Brown S R, Finan P J, Cawkwell L, Quirke P, Bishop D T

Abstract excerpt

BACKGROUND: Replication errors (RERs) characterise tumours of hereditary non-polyposis colorectal cancer (HNPCC). RER status may therefore improve identification of such families previously diagnosed by family history alone. AIMS: To assess RER and HNPCC frequency within a population of colorectal cancer patients and a regional population of family history defined (Amsterdam criteria) HNPCC families. METHODS:...

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Identifiers

PMID: 9824585
DOI: 10.1136/gut.43.4.553
PMCID: PMC1727271

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Source receipt: pubmed, retrieved 7 Sept 2026.

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