Article
Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma.
The American journal of pathology - 1 May 1996
Caduff R F, Johnston C M, Svoboda-Newman S M, Poy E L, Merajver S D, Frank T S
Abstract excerpt
Defective DNA mismatch repair in neoplasia is manifested by extra, aberrant bands within multiple microsatellite markers. The replication error (RER) phenotype is present in most colorectal and endometrial carcinomas in patients with the hereditary nonpolyposis colorectal carcinoma syndrome. In addition, a minority of sporadic colorectal and endometrial carcinomas are RER positive. RER in sporadic colorectal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
