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Article

A colorectal cell line with alterations in E-cadherin and epithelial biology may be an in vitro model of colitis.

Molecular pathology : MP - 1 Aug 1999

Perry I, Hardy R, Jones T, Jankowski J

Abstract excerpt

BACKGROUND: It has been shown previously in ulcerative colitis tissue that E-cadherin can occasionally be mutated in the extracellular domain early in neoplastic progression. E-cadherin is known to maintain differentiation and inhibits invasion in vivo. AIMS: To assess the mechanisms by which such dysfunction occurs. METHODS: Four human colorectal cancer cell lines, HCA-7 colonies 1, 3, 6, and 30, derived from a...

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Identifiers

PMID: 10694944
DOI: 10.1136/mp.52.4.231
PMCID: PMC395704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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