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Article

Effect of plasminogen activator inhibitor-1 deficiency on nutritionally-induced obesity in mice.

Thrombosis and haemostasis - 1 May 2005

Lijnen H Roger

Abstract excerpt

Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of tissue-type (t-PA) and urokinase-type (u-PA) plasminogen activator. Recent studies in murine models have yielded apparently conflicting data on a potential role of PAI-1 in adipose tissue development and obesity. To reinvestigate this issue, we have rederived PAI-1 deficient (PAI-1(-/-)) and wild-type (WT) mice and generated true...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15886793
DOI: 10.1160/TH05-01-0043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of plasminogen activator inhibitor-1 deficiency on nutritionally-induced obesity in mice.PMID 15886793Read ↗

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