Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An efficient and reliable multiplex PCR-SSCP mutation analysis test applied to the human E-cadherin gene.

Human mutation - 1 Jan 1997

Berx G, Nollet F, Strumane K, van Roy F

Abstract excerpt

The invasion suppressor gene E-CADHERIN (CDH1) is downregulated in a large variety of human carcinomas. Up to now, mutational analysis of the CDH1 gene has been described for 325 tumors derived from only four different tissue types. A simple but sensitive mutation detection assay is needed to screen many more tumor types, possibly bearing E-cadherin inactivating mutations. For that purpose, we developed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Mutational Analysis
Share to DNA Primers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Introns

Share to Mutation

Share to Point Mutation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 9195232
DOI: 10.1002/(SICI)1098-1004(1997)9:6<567::AID-HUMU11>3.0.CO;2-0

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An efficient and reliable multiplex PCR-SSCP mutation analysis test applied to the human E-cadherin gene.PMID 9195232Read ↗

Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online.Semantic proximity Read ↗

Mutations of the human E-cadherin (CDH1) gene.Semantic proximity Read ↗

The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression.Semantic proximity Read ↗

E-cadherin mutations and cell motility: a genotype-phenotype correlation.Semantic proximity Read ↗

E-cadherin polymorphisms and breast cancer susceptibility: a report from the Shanghai Breast Cancer Study.Semantic proximity Read ↗

A highly sensitive, fast, and economical technique for mutation analysis in hereditary breast and ovarian cancers.Semantic proximity Read ↗

Correlation between E-cadherin abnormal expressions in different types of cancer and the process of metastasis.Semantic proximity Read ↗

E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers.Semantic proximity Read ↗

Loss of Expression and Aberrant Methylation of the CDH1 (E-cadherin) Gene in Breast Cancer Patients from KashmirSemantic proximity Read ↗

Genomic PCR-SSCP analysis of the metastasis associated NM23-H1 (NME1) gene: a study on colorectal cancer.Semantic proximity Read ↗

Identification of an intronic single nucleotide polymorphism leading to allele dropout during validation of a CDH1 sequencing assay: implications for designing polymerase chain reaction-based assays.Semantic proximity Read ↗

Characterization of DNA polymorphisms in the E-cadherin gene (CDH1) promoter region.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.