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Article

The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression.

Breast cancer research : BCR - 1 Jan 2001

Berx G, Van Roy F

Abstract excerpt

E-cadherin is a cell-cell adhesion protein fulfilling a prominent role in epithelial differentiation. Data from model systems suggest that E-cadherin is a potent invasion/tumor suppressor of breast cancer. Consistent with this role in breast cancer progression, partial or complete loss of E-cadherin expression has been found to correlate with poor prognosis in breast cancer patients. The E-cadherin gene (CDH1) is...

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Source

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Identifiers

PMID: 11597316
DOI: 10.1186/bcr309
PMCID: PMC138690

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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