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Article

Apparent protection from instability of repeat sequences in cancer-related genes in replication error positive gastrointestinal cancers.

Oncogene - 29 May 1997

Simms L A, Zou T T, Young J, Shi Y Q, Lei J, Appel R, Rhyu M G, Sugimura H, Chenevix-Trench G, Souza R F, Meltzer S J, Leggett B A

Abstract excerpt

Genomic instability at simple repeated sequences has been observed in various types of human cancers and is considered an important mechanism in tumorigenesis. Alterations at microsatellite loci have been reported scattered throughout the genome. Recently, the transforming growth factor-beta receptor type II (TGF-beta RII) and the insulin-like growth factor II receptor (IGF-IIR) genes were shown to have...

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Share to Adenocarcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, p53

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Source

Identifiers

PMID: 9191061
DOI: 10.1038/sj.onc.1201094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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