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Article

Abnormal nucleotide repeat sequence in the TGF-betaRII gene in hepatocellular carcinoma and in uninvolved liver tissue.

The Journal of pathology - 1 Oct 2001

Enomoto A, Esumi M, Yamashita K, Takagi K, Takano S, Iwai S

Abstract excerpt

Replication error (RER)-related genetic alterations are associated with a subset of hepatocellular carcinomas (HCCs) with multiple primary cancers. This study investigated whether mutations in the nucleotide repeats of three putative target genes of RER are associated with hepatocarcinogenesis. The genes examined were those encoding transforming growth factor beta type II receptor (TGF-betaRII), BCL-2-associated...

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Share to bcl-2-Associated X Protein
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms, Multiple Primary

Share to Proto-Oncogene Proteins c-bcl-2

Share to Receptor, IGF Type 2

Share to Receptor, Transforming Growth Factor-beta Type II

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Source

Identifiers

PMID: 11673833
DOI: 10.1002/path.963

Genes

BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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