Microsatellite instability and mutations of p53 and TGF-beta RII genes in gastric cancer.

doi:10.1007/s004390050267

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Article

Microsatellite instability and mutations of p53 and TGF-beta RII genes in gastric cancer.

Human genetics - 1 Nov 1996

Renault B, Calistri D, Buonsanti G, Nanni O, Amadori D, Ranzani G N

Abstract excerpt

To investigate the molecular mechanism of gastric carcinogenesis, we analyzed genetic instability and p53 gene mutations in 40 primary gastric carcinomas. Tumor samples were from untreated patients with no family history suggestive of genetic predisposition to cancer. We screened six microsatelli...

Topics

DNA Mutational Analysis
Electrophoresis, Polyacrylamide Gel
Genes, p53
Humans
Microsatellite Repeats
Mutagenesis
Phenotype
Polymerase Chain Reaction
Protein Serine-Threonine Kinases
Receptor, Transforming Growth Factor-beta Type II
Receptors, Transforming Growth Factor beta
Stomach Neoplasms
Transforming Growth Factor beta

Source

Open in PubMed

Identifiers

PMID: 8882883
DOI: 10.1007/s004390050267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8882883-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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