Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis.

doi:10.1053/gast.1997.v112.pm9178696

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Article

Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis.

Gastroenterology - 1 Jun 1997

Strettell M D, Donaldson P T, Thomson L J, Santrach P J, Moore S B, Czaja A J, Williams R

Abstract excerpt

BACKGROUND & AIMS: In a recent study, we suggested that susceptibility to type 1 autoimmune hepatitis is associated with a six-amino acid motif, LLEQKR, within the DR beta polypeptide, but these data are in conflict with contemporary reports from Japan and Argentina. The purpose of the present st...

Topics

Adult
Aged
Alleles
Amino Acids
Autoimmune Diseases
Female
HLA Antigens
Hepatitis
Humans
Male
Middle Aged

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