Article
Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis.
Gastroenterology - 1 Jun 1997
Strettell M D, Donaldson P T, Thomson L J, Santrach P J, Moore S B, Czaja A J, Williams R
Abstract excerpt
BACKGROUND & AIMS: In a recent study, we suggested that susceptibility to type 1 autoimmune hepatitis is associated with a six-amino acid motif, LLEQKR, within the DR beta polypeptide, but these data are in conflict with contemporary reports from Japan and Argentina. The purpose of the present study was to reexamine this question in a large independent cohort of patients. METHODS: Eighty-six North American white...
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