Article
A genomewide DNA microsatellite association study of Japanese patients with autoimmune hepatitis type 1.
Hepatology (Baltimore, Md.) - 1 Feb 2007
Yokosawa Shuichi, Yoshizawa Kaname, Ota Masao, Katsuyama Yoshihiko, Kawa Shigeyuki, Ichijo Tetsuya, Umemura Takeji, Tanaka Eiji, Kiyosawa Kendo
Abstract excerpt
UNLABELLED: Genetic predisposition to type 1 autoimmune hepatitis (AIH) is linked mainly to HLA class II genes. We previously searched the whole HLA region for AIH susceptibility genes using microsatellite markers and found only HLA-DR/DQ to be a candidate region for this suspected multifactorial disease. As such, the aim of this study was to broaden our search and screen the whole genome for additional genes...
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