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Article

Human leukocyte antigen class II haplotypes affect clinical characteristics and progression of type 1 autoimmune hepatitis in Japan.

PloS one - 1 Jan 2014

Umemura Takeji, Katsuyama Yoshihiko, Yoshizawa Kaname, Kimura Takefumi, Joshita Satoru, Komatsu Michiharu, Matsumoto Akihiro, Tanaka Eiji, Ota Masao

Abstract excerpt

Although we earlier demonstrated that the human leukocyte antigen (HLA) DRB1*04:05 allele was associated with susceptibility to autoimmune hepatitis (AIH) in Japan, the precise relationship of HLA haplotype and the role of amino acid alignment with disease susceptibility and progression has not been fully clarified. We reinvestigated HLA class I A, B, and C and HLA class II DRB1, DQB1, and DPB1 alleles and...

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Source

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Identifiers

PMID: 24956105
DOI: 10.1371/journal.pone.0100565
PMCID: PMC4067340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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