Article
Genetic analysis of the HLA region of Japanese patients with type 1 autoimmune hepatitis.
Journal of hepatology - 1 Apr 2005
Yoshizawa Kaname, Ota Masao, Katsuyama Yoshihiko, Ichijo Tetsuya, Matsumoto Akihiro, Tanaka Eiji, Kiyosawa Kendo
Abstract excerpt
BACKGROUND/AIMS: Genetic predisposition to type 1 autoimmune hepatitis (AIH) is linked mainly to HLA-class II genes. The aim of this study is to scan the HLA region for additional genes which may contribute to type 1 AIH susceptibility. METHODS: We performed association analysis using HLA class I and II alleles and 18 polymorphic microsatellite markers distributed throughout the HLA region. We specifically...
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